Global Health Security Fund

GHIC has partnered with BARDA to use venture capital investments to accelerate the development and introduction of technologies and medical products to respond to and prevent health security threats. Through this partnership, BARDA intends to provide GHIC with up to $500 million in funding over the course of the 10-year agreement to support the creation of a Global Health Security venture investment portfolio.

The Global Health Security Fund is focused broadly on medical countermeasures that will better position the world to respond to or prevent public health emergencies, including vaccines, diagnostics, therapeutics, manufacturing platforms, and other critical technologies.

GHIC leverages its global health investment and commercialization experience while benefiting from BARDA’s scientific and technical input to help support important health security technologies. To amplify the impact of BARDA's funding, GHIC will mobilize additional capital from other investors for co-investment. As GHIC’s Global Health Security Fund companies generate investment returns, proceeds from BARDA’s investment capital will be recycled by GHIC into additional investments. These investments will also be designed to advance the goals of the partnership, further amplifying the mission impact of BARDA’s initial funding.

Learn more about BARDA and BARDA Ventures here.

Portfolio Investments

Aerska . Opens in new tab.

Global Health Security Fund

Intervention: Brain-targeted medicine delivery platform

Targets: Neurodegenerative diseases and neurotropic viral infections

Impact Objectives: Advance systemic delivery of medicines to the brain

Antheia . Opens in new tab.

Global Health Security Fund

Intervention: Biosynthesis Manufacturing Platform

Targets: Key Starting Materials (KSMs) and Active Pharmaceutical Ingredients (APIs)

Impact Objectives: Enhance resilience and security of the biopharmaceutical supply chain

Apriori Bio . Opens in new tab.

Global Health Security Fund

Intervention: Predictive vaccine design platform

Targets: Seasonal and pandemic respiratory viruses

Impact Objectives: Develop vaccines with improved protective efficacy by anticipating future virus strains and enable faster, more effective outbreak response

Biolinq . Opens in new tab.

Global Health Security Fund

Intervention: Device

Targets: Diabetes, pre-diabetes, other diseases

Impact Objectives: Improve management of various clinical conditions and detect exposure to multiple public health agents

BugSeq Bioinformatics . Opens in new tab.

Global Health Security Fund

Intervention: Bioinformatics platform

Targets: Pathogen agnostic

Impact Objectives: Automated analysis of pathogen sequencing data for surveillance and pathogen agnostic diagnostic applications

Centivax . Opens in new tab.

Global Health Security Fund

Intervention: Vaccine platform

Targets: Influenza and other viruses

Impact Objectives: Universal protection against seasonal and pandemic viral threats

Cytovale . Opens in new tab.

Global Health Security Fund

Intervention: Cellular host response diagnostic

Targets: Sepsis

Impact Objectives: Detection and treatment of sepsis at its earliest stages to reduce morbidity and mortality

Endpoint Health . Opens in new tab.

Global Health Security Fund

Intervention: Therapeutic + Companion Diagnostic

Targets: Sepsis, autoimmune and inflammatory diseases

Impact Objectives: Apply a precision medicine approach to the treatment of sepsis, one of the leading causes of morbidity and mortality related to health security threats